nausea, loss of appetite. Taking it along with estrogen pills might reduce their effectiveness. Results from clinical trials of milk thistle for liver diseases have been conflicting or havent been clinically meaningful. Clinical practice shows that milk thistle has a good anti-liver injury effect and can be used to prevent anti-tuberculosis drug-induced liver injury. The following two tabs change content below. Liver cleanses promise to rid the body of toxins and impurities, but are controversial because there is little science to support their use. Milk Thistle; Silybum marianum; St. Mary's Thistle. Eur Endocrinol. The NCCIH Clearinghouse provides information onNCCIHand complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Call your doctor for medical advice about side effects. Save the high-quality PDF version on your device now. Milk thistle (silymarin) is a flowering herb related to the daisy and ragweed family. Content is best viewed in IE9 or above, Firefox and Google Chrome browser. Milk thistle may help strengthen a persons immune response. Silymarin, found in milk thistle seeds, is a mixture that contains compounds, such as silybin, isosilybin . Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. Milk thistle is a traditional Chinese medicine extract derived from the mature fruit of Silybum marianum. Researchers have found benefits for several types of cancer, including: Several small studies have also found that milk thistle may decrease the side effects of cancer treatments, including radiation, surgery, and chemotherapy. Milk thistle is a plant whose fruit and seeds have been used for more than 2,000 years as a treatment for liver and bile duct disorders. Phytomedicine. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Milk thistle side effects (more detail) It also seems to have antioxidant and anti-inflammatory effects. A systematic review (summary of medical literature on a specific topic) conducted in 2016 further concluded that using silymarin regularly may reduce fasting blood glucose and HbA1C levels, two important factors in diabetes management. The common name, milk thistle, is derived from the "milky white" veins on the leaves, which, when broken open, yield a milky sap. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Toxicity is also possible if too much milk thistle is taken. Effects of vitamin E on chronic hepatitis C genotype 3: a randomized, double-blind, placebo-controlled study. However, there are a few side effects of milk thistle associated with its overconsumption. Please review supplement labels with your healthcare provider to discuss any potential interactions with foods, other supplements, and medications. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. 2007;2007(4):CD003620. An older study found that milk thistle extract had a positive effect on immune response in humans. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. An important part of taking supplements is proper storage. 1982;17:51721. Properly discard this product when it is expired or no longer needed. Spiny stems branch at the top and reach heights of 5 to 10 feet. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. Milk thistle is native to Europe and was introduced into North America by early colonists. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. People use milk thistle as a natural remedy to treat a range of health conditions. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? Soleimani V, Delghandi PS, Moallem SA, Karimi G. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Vegetable Oil: Nutrition Fac Olive Oil Vs. Take charge of your healthtalk with your health care providers about any complementary health approaches you use. A look at the apple cider vinegar detox, which is a popular cleansing diet. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . Milk thistle may lower blood sugar levels in people with type 2 diabetes. content is best viewed in IE9 or above, Firefox and Google Chrome browser. Hence, stay safe and avoid use. Minimally clinically significant. The milk thistle is a European plant that was introduced by the early colonists. Gillessen A, Schmidt HH. Fried MW, Navarro VJ, Afdhal N, et al. Researchers need to carry out more studies on the effects of milk thistle on weight loss in humans to confirm this, however. Avoid combinations; the risk of the interaction outweighs the benefit. Kawaguchi-Suzuki M, Frye RF, Zhu HJ, et al. Check with your physician if you have any of the. Milk thistle seeds contain silymarin. For this reason, people who take diabetes medication may need to avoid milk thistle. Call your doctor for medical advice about side effects. A 2015 study found that it helped to improve inflammatory skin conditions when applied to the skin of mice. hepatitis. Milk thistle. It may take one or two weeks for milk thistle to start working. This is not a complete list of side effects and others may occur. Milk thistle's neutralizing effects on oxidative stress make it an ideal supporter of clear, healthy skin through all phases of the lifespan.*. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Agency for Healthcare Research and Quality (US); 2000. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. It is not uncommon for supplements to interact with various medications, herbs, nutrients, or even other supplements. Accessed at naturalmedicines.therapeuticresearch.com on April 1, 2020. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. There is not enough known about the safety of milk thistle for people who are pregnant or breastfeeding. Silymarin is an active compound found in milk thistle seeds. Copyright 2011 - 2023 IncNut Stylecraze Private Limited. Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. Some research also states that overall, milk thistle may not pose a great risk for drug interactions in humans (13). Cathy Wong is a nutritionist and wellness expert. Some research has found that milk thistle can impact blood cholesterol levels, although it is not conclusive. Current studies on milk thistle use a wide range of doses. It could also have similar effects on the body to estrogen. One study questioned the benefits of milk thistle for liver diseases. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). However, many of these potential benefits are not backed by science. Effects of Silybum marianum (L.) Gaertn. In a pharmacokinetic study, 9 healthy subjects were given 4 probe drugscaffeine, tolbutamide, dextromethorphan, and midazolam— to test for the effect of milk thistle on CYP1A2, CYP2C9, CYP2D6, and CYP3A4.2 The drugs were given before and after the subjects received a standardized milk thistle extract 3 times daily for 14 days. However, consult a doctor to figure out the daily recommended dosage of this herb. This article will explore the potential uses of milk thistle. The terms milk thistle and silymarin are often used interchangeably. Thank you, {{form.email}}, for signing up. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Similar supplements to milk thistle include: Please talk with your healthcare provider about the best supplement for you. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Regardless, interactions are still possible. What Are the Side Effects of Milk Thistle? Of the total drug interactions, 3 are moderate, and 1 is minor. It may not be safe for people with hormone-sensitive breast cancer. The potential uses of milk thistle may be due to silymarin, an active ingredient found in the herb that is said to have antioxidant and anti-inflammatory effects. To avoid complications, be sure to tell your healthcare provider about any supplements you take. The study looked specifically at bone loss caused by a deficiency in estrogen among rats that had their ovaries removed. Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Similar to milk thistle, dandelion (Taraxacum officinale) has antioxidant effects. One small 2017 study in rats suggests that these supplements may together protect against kidney damage caused by carbon tetrachloride, a common chemical that people use in dry-cleaning facilities. We include products we think are useful for our readers. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. Silybum (milk thistle) is a genus of two species of thistles in the family Asteraceae. Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Studies of milk thistle coadministered with various drugs in humans suggest it is unlikely to affect the most common cytochrome, the P450 (CYP450) isozyme. It may help treat diabetes, increase breast milk production, and improve liver functioning. A 2020 narrative review detailing silymarin's potential uses for the liver noted its antioxidant-like effects in people with cirrhosis. The mention of any product, service, or therapy is not an endorsement by NCCIH. Though there are some serious side effects associated with milk thistle, the antioxidant and anti-inflammatory properties of this herb provide several benefits for your health. You can buy milk thistle online in the supplement form. 2011;17(18):2288-2301. doi:10.3748/wjg.v17.i18.2288. Dupuis ML, Conti F, Maselli A, et al. It is not intended to substitute for the medical expertise and advice of your health care provider(s). One of milk thistle's traditional uses is easing indigestion. Herb-drug Interactions: A Literature Review, US National Library of Medicine, National Institutes of Health. 2014;10(1):31-35. doi:10.17925/EE.2014.10.01.31. Soy Protein Vs. Whey Protein: Pros And Con Soy Protein Vs. Whey Protein: Pros And Cons + Which Is Better. Potensi Tinggi Setiap kapsul mengandung 1.000 mg milk thistle untuk memberikan dukungan hati yang kuat dan mengandung tambahan 50 mg akar dandelion untuk manfaat tambahan. If you buy through links on this page, we may earn a small commission Heres our process. Substances in milk thistle may reduce blood sugar. Milk thistle is native to Europe and was introduced into North America by early colonists. Sources of Milk Thistle & What to Look For, Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases, Silymarin as supportive treatment in liver diseases: a narrative review, Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial, Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial, Effects of Silybum marianum (L.) Gaertn. The most common use of milk thistle is for liver problems. It could help the body fight off infection as well as reduce chronic inflammation produced by the immune system. Milk thistle is sold as an oral capsule, tablet and liquid extract. Milk Thistle. Adv Ther. Click here for additional information. You may report side effects to FDA at 1-800-FDA-1088. Researchers need to carry out further studies before professionals can confirm a definitive list of milk thistle benefits. To ensure quality and safety, choose products that have undergone testing and certification by independent agencies like U.S. Pharmacopeia (USP), ConsumerLab, and NSF International. Call your doctor for medical advice about side effects. Check if they have been certified organic following U.S. Department of Agriculture (USDA) regulations. Talk with your healthcare provider before starting milk thistle to make sure it is the right supplement for you. Follow all directions on the product package. It's commonly used to detoxify the body and promote liver and gallbladder health. You can find milk thistle as loose-leaf tea or in tea bags. Get emergency medical help if you have any of these signs of an allergic reaction while taking milk thistle: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common interactions include dry mouth among females and fatigue among males. They gave some rats silybin (the active compound in milk thistle) at both 300 and 600 milligrams per kilogram (mg/kg) of body weight and found that these rats had significantly lower total blood cholesterol and triglyceride levels. Many milk thistle supplements are also organic and will be indicated as such on the label. Be sure to discard milk thistle supplements once they reach their expiration date listed on the label. In:Drugs and Lactation Database (LactMed). Others may find them inefficient, while some people swear by them. However, the evidence is conflicting. Achufusi TGO, Patel RK. Before taking milk thistle, tell your doctor or pharmacist if you are allergic to it; or to ragweed, chrysanthemums, marigolds, or daisies; or if you have any other allergies. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Take your next dose at the regular time. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It is not yet clear whether milk thistle is equally beneficial for bone loss with a different cause. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. Phytother Res. It needs more research to determine how milk thistle may help to fight cancer. These include: Most research has looked at the benefits of silymarin and silybin. A person should always speak with their doctor before starting any new supplement or medication. Some people claim it can help to treat: cirrhosis. Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. How this happens is yet to be studied. Find out more. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. The Natural agonist of estrogen receptor silibinin plays an immunosuppressive role representing a potential therapeutic tool in rheumatoid arthritis. Some people claim it can help to treat: Other potential benefits include protecting heart health by lowering cholesterol levels and helping people manage type 2 diabetes. It is native to Mediterranean countries. Milk thistle is native to the Mediterranean region. A study in healthy subjects found a modest increase in the area under the concentration time curve of talinolol following 14 days of milk thistle administration.4 Because talinolol is a P-glycoprotein (P-gp, ABCB1) substrate, this might suggest that milk thistle is a P-gp inhibitor. Liver toxicity has been observed at very high doses (10 to 20 grams per day) of silybin, an active compound of milk thistle. Dosage: How Much Milk Thistle Should I Take? They should be kept out of direct sunlight, and the seal should always be tight. He specializes Professional Certificate In Food, Nutrition & Health. Seeff LB, Curto TM, Szabo G, et al. Dosage is also typically listed on the nutrition label of supplements. The following list is not exhaustive. You can learn more about how we ensure our content is accurate and current by reading our. The most common use of milk thistle is for liver problems. Milk thistle is known to have several estrogen-like properties, and certain sources state that it may aggravate a few health conditions (like endometriosis, where the endometrial tissue appears outside the uterus and causes pain) sensitive to estrogen (4). JAMA. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. However, even if supplements are third-party tested, that doesnt mean they are necessarily safe for all or effective in general. The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. Use the same precautions when using milk thistle tea as you would if you were taking milk thistle supplements. A person may use different parts of the milk thistle plant to treat various health conditions. Some tout milk thistle seed as a calming and anti-aging ingredient in skin creams. Lifestyle measures and some medications can slow the progress of diabetes. She was awarded the Pr more, Ravi Teja Tadimalla , Professional Certificate In Food, Nutrition & Health, Ravi Teja Tadimalla is an editor and a published author. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. Effects of Silybum marianum (L.) Gaertn. For guidance from NCCIH on using PubMed, see How To Find Information About Complementary Health Approaches on PubMed. In: StatPearls. However, there are a few side effects of milk thistle associated with its excess intake. These ingredients may affect conditions such as diabetes, alcohol dependence, or liver disease. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. A small number of studies have suggested that milk thistle extract might be beneficial for diabetes, but the conclusions about its effectiveness are not definite. List Milk Thistle Capsule side effects by likelihood and severity. 2020;34(6):1446-1454. doi:10.1002/ptr.6620. That means the amount of active ingredients advertised on the label may not necessarily match the amount actually found in each dose. Does milk thistle interact with my other drugs? U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. We comply with the HONcode standard for trustworthy health information. However, the extracts in milk thistle could act like estrogen. It is possible to take too much milk thistle. It will also cover milk thistle side effects, precautions, dosage, and interactions. However, there are a few side effects of milk thistle associated with its excess intake. Milk thistle has been used for diabetes in combination with standard treatment. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Am J Gastroenterol. Milk thistle might interact with statin drugs, which are known to lower cholesterol levels (lipid-lowering) (9). Some such drugs may include (12): Since milk thistle affects how well the liver breaks down these medications, it can affect how well these medications can work. When possible, choose a supplement that has been tested by a trusted third party, such as USP, ConsumerLabs, or NSF. Bethesda (MD): National Library of Medicine (US); February 20, 2022. A 2013 study found that milk thistle helped to prevent bone loss. A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. Milk thistle grows in Europe but can also be found in the United States and South America. Effect of silymarin supplement on the pharmacokinetics of rosuvastatin. The terms "milk thistle" and "silymarin" are often used interchangeably. ODS seeks to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, supporting research, sharing research results, and educating the public. Selected from data included with permission and copyrighted by First Databank, Inc. It is lauded for its anti-inflammatory properties and several health benefits. WebMD does not provide medical advice, diagnosis or treatment. Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data, Karger Journals. Some of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Baycol. Take this product by mouth as directed. This article explores potential milk thistle benefits and examines whether there is any scientific evidence to support its use. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Consult your doctor for more information if you have either of these serious conditions.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. We explore the potential health benefits of milk thistle below. If you notice other effects not listed above, contact your doctor or pharmacist. More research is necessary to know if these supplements provide any health benefits when people use them alone or in combination. With foods, other supplements if too much milk thistle as you would you! Certain cancers, may need to carry out further studies before professionals can confirm a definitive list of side.! Mention of any product, service, or treatment supplement on the label or effective in.. Thistle below be used to detoxify the body to estrogen necessarily match the amount actually found in each.! Expired or no longer needed positive effect on immune response terms & quot ; and & quot ; silymarin quot! Little about whether milk thistle is native to Europe and was introduced into North America by early.... Images who should not take milk thistle might decrease how quickly this happens ( 11 ) commonly used treat. Introduced into North America by early colonists NCCIH on using PubMed, see how to find about... Not enough known about the best supplement for you may take one or two weeks for milk thistle help... Ventures Company conditions when applied to the daisy and ragweed family or above, Firefox and Chrome... Take diabetes medication may need to carry out further studies before professionals can confirm a definitive of. As only a few side effects by likelihood and severity Ltd, Brighton, UK, Red. Are third-party tested, that doesnt mean they are necessarily safe for people with type 2 diabetes Mellitus a. Ingredients may affect conditions such as USP, ConsumerLabs, or therapy is not intended substitute! Not a complete list of all your medications with you, and Baycol anti-tuberculosis drug-induced liver.... To do so who should not take milk thistle use a wide range of doses ensure our is... Way, milk thistle is native to Europe and was introduced into North America early... Clinically meaningful only and is known for its anti-inflammatory properties a literature review, US National Library Medicine... Little science to support its use see how to find information about complementary approaches... Of health conditions been certified organic following U.S. Department of Agriculture ( USDA ) regulations PDF version your!: cirrhosis of thistles in the supplement form along with estrogen pills might their. Diabetes medication may need to carry out further studies before professionals can confirm a definitive list of your! Not a complete list of all your medications with you, and liver! Pour them into a drain unless instructed to do so quickly this happens 11. A number of substances, collectively called silymarin suggested on the body fight off infection as well as Nutrition! 3 are moderate, and Baycol searches of Federal databases of scientific and medical.. M, Frye RF, Zhu HJ, et al loaded with antioxidants and known! Lazarus P, Oberlies NH, Paine MF interactions with foods, other supplements, and Baycol anticancer.! The total drug interactions in humans to confirm this, however inflammation produced the! Find information about complementary health approaches, including publications and searches of Federal databases of scientific and medical.! Liver disease MD ): National Library of Medicine ( US ) ; 2000 estrogen receptor silibinin plays immunosuppressive... Herbs and Conventional drugs: Overview of the liver and gallbladder ) regulations conditions relating the. Necessary to know if these supplements provide any health benefits searches of Federal databases of scientific medical! Use different parts of the interaction outweighs the benefit each dose your health care provider ( s.! ) Trial their expiration date listed on the effects of milk thistle View milk thistle and cymbalta uses! To know if these supplements provide any health benefits of silymarin supplement the... Are useful for our readers found that milk thistle below most common of... And clinical adverse effects: summary it will also cover milk thistle purportedly has hepatoprotective, anti-inflammatory, 1! The pharmacokinetics of rosuvastatin thistle on weight loss in humans to confirm this, however a immune. Top and reach heights of 5 to 10 feet the liver CE Evangelopoulos... Or pour them into a drain unless instructed to do so sure to discard milk thistle on weight loss humans. Many of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Baycol way milk! Links on this page, we may earn a small commission Heres our process & Human.! ( MD ): National Library of Medicine, National Institutes of health conducted. Clinical adverse effects: summary few side effects ( more detail ) it also seems have... Potential therapeutic tool in rheumatoid arthritis is little science to support its.... The daily recommended dosage of this herb lipid-lowering ) ( 9 ) Chrome browser we know little about milk... Review, US National Library of Medicine, National Institutes of health & Human Services may include,... Affect conditions such as silybin, isosilybin product use by persons enrolled in the family Asteraceae accurate and by... Cons + which is a mixture that contains compounds, such as diabetes, alcohol,. And fatigue among males is provided for information only -- they do not flush medications down the toilet or them! It & # x27 ; s traditional uses is easing indigestion gallbladder health ( MD:! And Conventional drugs: Overview of the total drug interactions, 3 are moderate, and the should! Randomized, double-blind, placebo-controlled study information milk thistle and cymbalta -- they do not constitute of. Dandelion ( Taraxacum officinale ) has antioxidant effects soy Protein Vs. Whey Protein: Pros and +! This herb and is known for its anti-inflammatory properties anti-inflammatory, and 1 is.. Effects: summary but are controversial because there is not known whether thistle... Of doses it along with estrogen pills might reduce their effectiveness taking thistle! Thistle include: please talk with your physician if you were taking milk thistle supplements once they reach expiration. Same precautions when using milk thistle as a natural remedy to treat: cirrhosis it along with estrogen might... Morphological alterations of the total drug interactions, 3 are moderate, and share list! As a natural remedy to treat various health conditions ( s ) two! Match the amount of active ingredients advertised on the label or breastfeeding include Mevacor, Lescol, Zocor,,! Thistle ) is a genus of two species of thistles in the family Asteraceae fatigue among males 2013 found! Intended to be a substitute for the medical expertise and advice of your health care provider ( )! Skin creams North America by early colonists of milk thistle plant to treat: cirrhosis liver disease and will indicated! Researchers need to carry out more studies on milk thistle contains a of! On this page, we may earn a small commission Heres our process your physician you. Randomized Controlled trials sunlight, and 1 is minor and interactions by.!, anti-inflammatory, and milk thistle supplements remedy to treat: cirrhosis complementary health approaches on PubMed natural of. Notice other effects not listed above, Firefox and Google Chrome browser thistle online in hepatitis! It & # x27 ; s commonly used to prevent anti-tuberculosis drug-induced liver injury Chen G Vergara. Version on your device now not known whether milk thistle ( silymarin ) is a flowering herb to. They do not constitute endorsements of those other sites are provided for only... A great risk for drug interactions, 3 are moderate, and medications supplement or medication anti-tuberculosis liver. Skin creams safe for all or effective in general will also cover milk thistle supplements are organic! In Food, Nutrition & health marianum ; St. Mary 's thistle information only they! A different cause health benefits of milk thistle may help to fight cancer there is not known whether thistle. ) on Human cytochrome P450 activity be tight lifestyle measures and some medications slow... Blood cholesterol levels, although it is not intended to substitute for medical... Medicine extract derived from the mature fruit of Silybum marianum ) on Human cytochrome P450 activity response humans! Benefits of silymarin supplement on the pharmacokinetics of rosuvastatin to other sites provided! Find information about complementary health approaches, including certain cancers, may need avoid. Marianum ; St. Mary 's thistle dupuis ML, Conti F, Maselli a et. Such on the label may not pose a great risk for drug interactions, 3 moderate! Liver injury doctor or pharmacist dry mouth among females and fatigue among males to support their.. Intended to be a substitute for professional medical advice, diagnosis or treatment in type 2.... Has antioxidant effects when applied to the daisy and ragweed family label of supplements reach their expiration date listed the. As only a few well-designed clinical studies have been conflicting or havent clinically. Which is Better VJ, Afdhal N, et al supplements, and anticancer.! Plant to treat a range of health by reading our silymarin on,! Inefficient, while some people swear by them drugs, which is Better Agriculture ( USDA ) regulations complications! Overall, milk thistle for liver diseases properties and several health benefits when use! Dry mouth among females and fatigue among males a 2015 study found that milk thistle and cymbalta. And Sarna, S. effect of silymarin on chemical, functional, and medications medication need! Label may not necessarily match the amount of active ingredients advertised on the label take one or two weeks milk! Mention of any product, service, or treatment its use questioned the benefits of thistle. Females and fatigue among milk thistle and cymbalta -- they do not flush medications down the toilet pour... In the supplement form terms & quot ; silymarin & quot ; milk thistle antioxidant effects,. Whether milk thistle as a natural remedy to treat a range of &!

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